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q-value Chart
Detail
Domain Gene Set Term Gene Num Input Gene Num Hit Gene Num log10(p value) log10(q value)
Domain Gene Set Term Gene Num Input Gene Num Hit Gene Num log10(p value) log10(q value)
GO_Biological_Processes GO_AMIDE_BIOSYNTHETIC_PROCESS 507 39 7 -4.39334 -1.50685
GO_Biological_Processes GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS 1024 39 9 -4.01221 -1.42675
GO_Biological_Processes GO_POSITIVE_REGULATION_OF_NF_KAPPAB_TRANSCRIPTION_FACTOR_ACTIVITY 132 39 4 -3.95562 -1.54625
GO_Biological_Processes GO_ORGANIC_CYCLIC_COMPOUND_CATABOLIC_PROCESS 427 39 6 -3.85722 -1.57279
GO_Biological_Processes GO_TRANSLATIONAL_INITIATION 146 39 4 -3.78682 -1.59930
GO_Biological_Processes GO_CELLULAR_AMIDE_METABOLIC_PROCESS 727 39 7 -3.42352 -1.31518
GO_Biological_Processes GO_POSITIVE_REGULATION_OF_PROTEOLYSIS 363 39 5 -3.23808 -1.19669
GO_Biological_Processes GO_CELLULAR_CATABOLIC_PROCESS 1322 39 9 -3.18572 -1.20232
GO_Biological_Processes GO_PEPTIDE_METABOLIC_PROCESS 571 39 6 -3.18240 -1.25015
GO_Biological_Processes GO_GAMETE_GENERATION 595 39 6 -3.08905 -1.20256
GO_Biological_Processes GO_RNA_CATABOLIC_PROCESS 227 39 4 -3.06130 -1.21621
GO_Biological_Processes GO_POSITIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY 228 39 4 -3.05421 -1.24690
GO_Biological_Processes GO_MRNA_METABOLIC_PROCESS 611 39 6 -3.02921 -1.25666
GO_Biological_Processes GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM 104 39 3 -3.00125 -1.26089
GO_Biological_Processes GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION 1733 39 10 -2.94835 -1.23795
GO_Biological_Processes GO_RRNA_METABOLIC_PROCESS 255 39 4 -2.87442 -1.19205
GO_Biological_Processes GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_NONSENSE_MEDIATED_DECAY 118 39 3 -2.84312 -1.18708
GO_Biological_Processes GO_ORGANONITROGEN_COMPOUND_METABOLIC_PROCESS 1796 39 10 -2.82988 -1.19866
GO_Biological_Processes GO_POSITIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS 1805 39 10 -2.81340 -1.20567
GO_Biological_Processes GO_MACROMOLECULE_CATABOLIC_PROCESS 926 39 7 -2.80448 -1.21902
GO_Biological_Processes GO_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM 123 39 3 -2.79142 -1.22715
GO_Biological_Processes GO_DNA_DAMAGE_RESPONSE_DETECTION_OF_DNA_DAMAGE 36 39 2 -2.67634 -1.13227
GO_Biological_Processes GO_MULTI_ORGANISM_METABOLIC_PROCESS 138 39 3 -2.64881 -1.12405
GO_Biological_Processes GO_SEXUAL_REPRODUCTION 730 39 6 -2.63518 -1.12890
GO_Biological_Processes GO_ERBB2_SIGNALING_PATHWAY 39 39 2 -2.60742 -1.11886
GO_Biological_Processes GO_RIBOSOME_BIOGENESIS 308 39 4 -2.57570 -1.10419
GO_Biological_Processes GO_MULTICELLULAR_ORGANISM_REPRODUCTION 768 39 6 -2.52532 -1.07019
GO_Biological_Processes GO_PROTEIN_TARGETING_TO_MEMBRANE 157 39 3 -2.49033 -1.05099
GO_Molecular_Functions GO_RNA_BINDING 1598 39 13 -5.38363 -3.35021
GO_Molecular_Functions GO_TRANSLATION_FACTOR_ACTIVITY_RNA_BINDING 89 39 3 -3.19784 -1.46545
GO_Molecular_Functions GO_TRANSLATION_ELONGATION_FACTOR_ACTIVITY 20 39 2 -3.18864 -1.63233
GO_Molecular_Functions GO_POLY_A_RNA_BINDING 1170 39 8 -2.87564 -1.44428
GO_Cellular_Components GO_CYTOSOLIC_SMALL_RIBOSOMAL_SUBUNIT 44 39 3 -4.10554 -2.11877
GO_Cellular_Components GO_SMALL_RIBOSOMAL_SUBUNIT 68 39 3 -3.54120 -1.85546
GO_Cellular_Components GO_CYTOSOLIC_PART 223 39 4 -3.09005 -1.58040
GO_Cellular_Components GO_NUCLEOLUS 848 39 7 -3.02613 -1.64142
GO_Cellular_Components GO_CYTOSOLIC_RIBOSOME 113 39 3 -2.89720 -1.60940
GO_Cellular_Components GO_RIBOSOMAL_SUBUNIT 163 39 3 -2.44454 -1.23592
All_Canonical_Pathways REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX 74 39 6 -8.28832 -5.98512
All_Canonical_Pathways REACTOME_TRANSLATION 222 39 8 -8.13524 -6.13307
All_Canonical_Pathways REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S 84 39 6 -7.95301 -6.12693
All_Canonical_Pathways REACTOME_PEPTIDE_CHAIN_ELONGATION 153 39 6 -6.39552 -4.69438
All_Canonical_Pathways REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 176 39 6 -6.03864 -4.43441
All_Canonical_Pathways REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 179 39 6 -5.99576 -4.47071
All_Canonical_Pathways REACTOME_METABOLISM_OF_RNA 330 39 7 -5.60324 -4.14514
All_Canonical_Pathways REACTOME_METABOLISM_OF_PROTEINS 518 39 8 -5.33314 -3.93303
All_Canonical_Pathways REACTOME_METABOLISM_OF_MRNA 284 39 6 -4.84205 -3.49309
All_Canonical_Pathways REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION 169 39 5 -4.79626 -3.49307
All_Canonical_Pathways REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 176 39 5 -4.71127 -3.44947
All_Canonical_Pathways REACTOME_INFLUENZA_LIFE_CYCLE 203 39 5 -4.41414 -3.19013
All_Canonical_Pathways REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION 9 39 2 -3.90538 -2.71613
All_Canonical_Pathways REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS 10 39 2 -3.80899 -2.65192
All_Canonical_Pathways REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL 11 39 2 -3.72236 -2.59525
All_Canonical_Pathways REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY 11 39 2 -3.72236 -2.59525
All_Canonical_Pathways REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING 12 39 2 -3.64370 -2.57095
All_Canonical_Pathways REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES 12 39 2 -3.64370 -2.57095
All_Canonical_Pathways REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR 12 39 2 -3.64370 -2.57095
All_Canonical_Pathways REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX 14 39 2 -3.50524 -2.50307
All_Canonical_Pathways REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING 14 39 2 -3.50524 -2.50307
All_Canonical_Pathways REACTOME_P75NTR_SIGNALS_VIA_NFKB 14 39 2 -3.50524 -2.50307
All_Canonical_Pathways REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX 14 39 2 -3.50524 -2.50307
All_Canonical_Pathways REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON 14 39 2 -3.50524 -2.50307
All_Canonical_Pathways REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS 15 39 2 -3.44361 -2.53835
All_Canonical_Pathways REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION 16 39 2 -3.38613 -2.49791
All_Canonical_Pathways REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR 18 39 2 -3.28166 -2.40983
All_Canonical_Pathways REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA 18 39 2 -3.28166 -2.40983
All_Canonical_Pathways KEGG_RIBOSOME 88 39 3 -3.21216 -2.37137
All_Canonical_Pathways REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY 20 39 2 -3.18864 -2.36256
All_Canonical_Pathways REACTOME_SIGNALING_BY_ERBB4 90 39 3 -3.18368 -2.37185
All_Canonical_Pathways REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING 23 39 2 -3.06583 -2.26778
All_Canonical_Pathways REACTOME_SIGNALING_BY_ERBB2 101 39 3 -3.03807 -2.25339
All_Canonical_Pathways REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN 25 39 2 -2.99286 -2.22114
All_Canonical_Pathways REACTOME_EGFR_DOWNREGULATION 25 39 2 -2.99286 -2.22114
All_Canonical_Pathways REACTOME_FANCONI_ANEMIA_PATHWAY 25 39 2 -2.99286 -2.22114
All_Canonical_Pathways REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS 26 39 2 -2.95862 -2.22362
All_Canonical_Pathways REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B 26 39 2 -2.95862 -2.22362
All_Canonical_Pathways REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS 27 39 2 -2.92571 -2.21358
All_Canonical_Pathways REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION 27 39 2 -2.92571 -2.21358
All_Canonical_Pathways REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT 27 39 2 -2.92571 -2.21358
All_Canonical_Pathways REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A 28 39 2 -2.89405 -2.21410
All_Canonical_Pathways REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING 31 39 2 -2.80564 -2.13591
All_Canonical_Pathways REACTOME_INNATE_IMMUNE_SYSTEM 279 39 4 -2.73136 -2.07162
All_Canonical_Pathways REACTOME_NEGATIVE_REGULATION_OF_FGFR_SIGNALING 37 39 2 -2.65272 -2.00274
All_Canonical_Pathways REACTOME_G1_PHASE 38 39 2 -2.62976 -1.98932
All_Canonical_Pathways REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER 38 39 2 -2.62976 -1.98932
All_Canonical_Pathways REACTOME_APOPTOSIS 148 39 3 -2.56267 -1.94071
All_Canonical_Pathways REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION 46 39 2 -2.46591 -1.85291
All_Canonical_Pathways REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 48 39 2 -2.42958 -1.82535
All_Canonical_Pathways REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 51 39 2 -2.37793 -1.78230
All_Canonical_Pathways REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 51 39 2 -2.37793 -1.78230
All_Canonical_Pathways REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT 51 39 2 -2.37793 -1.78230
All_Canonical_Pathways REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G 52 39 2 -2.36141 -1.79061
All_Canonical_Pathways REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 53 39 2 -2.34522 -1.78239
All_Canonical_Pathways REACTOME_CIRCADIAN_CLOCK 53 39 2 -2.34522 -1.78239
All_Canonical_Pathways KEGG_CALCIUM_SIGNALING_PATHWAY 178 39 3 -2.33762 -1.79030
All_Canonical_Pathways REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 56 39 2 -2.29850 -1.75873
All_Canonical_Pathways REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX 56 39 2 -2.29850 -1.75873
All_Canonical_Pathways REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE 57 39 2 -2.28351 -1.75846
All_Canonical_Pathways REACTOME_REGULATION_OF_APOPTOSIS 58 39 2 -2.26878 -1.75092
All_Canonical_Pathways REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE 60 39 2 -2.24012 -1.72931
All_Canonical_Pathways REACTOME_ER_PHAGOSOME_PATHWAY 61 39 2 -2.22615 -1.72230
All_Canonical_Pathways REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX 63 39 2 -2.19893 -1.70192
All_Canonical_Pathways REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS 64 39 2 -2.18566 -1.69538
All_Canonical_Pathways REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C 64 39 2 -2.18566 -1.69538
All_Canonical_Pathways REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ 65 39 2 -2.17261 -1.69548
All_Canonical_Pathways REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX 65 39 2 -2.17261 -1.69548
All_Canonical_Pathways REACTOME_SIGNALING_BY_WNT 65 39 2 -2.17261 -1.69548
All_Canonical_Pathways REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 66 39 2 -2.15976 -1.70166
All_Canonical_Pathways REACTOME_ORC1_REMOVAL_FROM_CHROMATIN 67 39 2 -2.14711 -1.69517
All_Canonical_Pathways REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 212 39 3 -2.12784 -1.68197
All_Canonical_Pathways REACTOME_SIGNALING_BY_NOTCH1 70 39 2 -2.11033 -1.67046
All_Canonical_Pathways REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 72 39 2 -2.08672 -1.65275
All_Canonical_Pathways REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE 72 39 2 -2.08672 -1.65275
All_Canonical_Pathways REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS 73 39 2 -2.07517 -1.65279
All_Canonical_Pathways REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS 73 39 2 -2.07517 -1.65279
All_Canonical_Pathways REACTOME_TRIF_MEDIATED_TLR3_SIGNALING 74 39 2 -2.06379 -1.65268
All_Canonical_Pathways REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION 76 39 2 -2.04150 -1.63593
All_Canonical_Pathways REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION 77 39 2 -2.03058 -1.63048
All_Canonical_Pathways REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 81 39 2 -1.98837 -1.59366
All_Canonical_Pathways REACTOME_M_G1_TRANSITION 81 39 2 -1.98837 -1.59366
All_Canonical_Pathways REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE 83 39 2 -1.96808 -1.58397
All_Canonical_Pathways REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS 84 39 2 -1.95813 -1.57922
All_Canonical_Pathways REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE 85 39 2 -1.94831 -1.57453
All_Canonical_Pathways REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 251 39 3 -1.92878 -1.56008
All_Canonical_Pathways REACTOME_SYNTHESIS_OF_DNA 92 39 2 -1.88278 -1.51910
All_Canonical_Pathways REACTOME_ACTIVATED_TLR4_SIGNALLING 93 39 2 -1.87385 -1.51514
All_Canonical_Pathways REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR 97 39 2 -1.83913 -1.48533
All_Canonical_Pathways REACTOME_SIGNALING_BY_NOTCH 103 39 2 -1.78982 -1.44087
All_Canonical_Pathways REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 104 39 2 -1.78190 -1.43775
All_Canonical_Pathways REACTOME_S_PHASE 109 39 2 -1.74349 -1.40408
All_Canonical_Pathways REACTOME_SIGNALING_BY_EGFR_IN_CANCER 109 39 2 -1.74349 -1.40408
All_Canonical_Pathways BIOCARTA_DNAFRAGMENT_PATHWAY 10 39 1 -1.72699 -1.39692
All_Canonical_Pathways BIOCARTA_RNA_PATHWAY 10 39 1 -1.72699 -1.39692
All_Canonical_Pathways REACTOME_SIGNALING_BY_FGFR 112 39 2 -1.72134 -1.40041
All_Canonical_Pathways REACTOME_G1_S_TRANSITION 112 39 2 -1.72134 -1.40041
All_Canonical_Pathways REACTOME_DNA_REPAIR 112 39 2 -1.72134 -1.40041
All_Canonical_Pathways BIOCARTA_SET_PATHWAY 11 39 1 -1.68600 -1.37844
All_Canonical_Pathways BIOCARTA_EIF2_PATHWAY 11 39 1 -1.68600 -1.37844
All_Canonical_Pathways REACTOME_TOLL_RECEPTOR_CASCADES 118 39 2 -1.67889 -1.38001
All_Canonical_Pathways REACTOME_CELL_CYCLE_CHECKPOINTS 124 39 2 -1.63871 -1.34411
All_Canonical_Pathways REACTOME_HIV_LIFE_CYCLE 125 39 2 -1.63221 -1.34185
All_Canonical_Pathways REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR 126 39 2 -1.62578 -1.33961
All_Canonical_Pathways REACTOME_SIGNALING_BY_FGFR_IN_DISEASE 127 39 2 -1.61939 -1.33739
All_Canonical_Pathways REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION 13 39 1 -1.61424 -1.33635
All_Canonical_Pathways REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING 13 39 1 -1.61424 -1.33635
All_Canonical_Pathways REACTOME_MEMBRANE_TRAFFICKING 129 39 2 -1.60679 -1.33702
All_Canonical_Pathways REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 132 39 2 -1.58828 -1.32251
All_Canonical_Pathways KEGG_INSULIN_SIGNALING_PATHWAY 137 39 2 -1.55843 -1.29662
All_Canonical_Pathways REACTOME_MITOTIC_G1_G1_S_PHASES 137 39 2 -1.55843 -1.29662
All_Canonical_Pathways REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE 15 39 1 -1.55289 -1.29892
All_Canonical_Pathways PID_ERBB_NETWORK_PATHWAY 15 39 1 -1.55289 -1.29892
All_Canonical_Pathways KEGG_OTHER_GLYCAN_DEGRADATION 16 39 1 -1.52526 -1.27897
All_Canonical_Pathways BIOCARTA_EIF_PATHWAY 16 39 1 -1.52526 -1.27897
All_Canonical_Pathways REACTOME_IMMUNE_SYSTEM 933 39 5 -1.52034 -1.28160
All_Canonical_Pathways REACTOME_INFLAMMASOMES 17 39 1 -1.49933 -1.26432
All_Canonical_Pathways REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS 18 39 1 -1.47491 -1.24359
All_Canonical_Pathways SA_CASPASE_CASCADE 19 39 1 -1.45183 -1.22418
All_Canonical_Pathways REACTOME_CGMP_EFFECTS 19 39 1 -1.45183 -1.22418
All_Canonical_Pathways REACTOME_INTERFERON_SIGNALING 159 39 2 -1.43987 -1.21946
All_Canonical_Pathways REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING 20 39 1 -1.42995 -1.21311
All_Canonical_Pathways BIOCARTA_IGF1MTOR_PATHWAY 20 39 1 -1.42995 -1.21311
All_Canonical_Pathways BIOCARTA_MITOCHONDRIA_PATHWAY 21 39 1 -1.40916 -1.19938
All_Canonical_Pathways REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING 22 39 1 -1.38935 -1.18307
All_Canonical_Pathways BIOCARTA_HER2_PATHWAY 22 39 1 -1.38935 -1.18307
All_Canonical_Pathways REACTOME_MITOTIC_M_M_G1_PHASES 172 39 2 -1.37803 -1.17863
All_Canonical_Pathways BIOCARTA_CASPASE_PATHWAY 23 39 1 -1.37044 -1.17446
All_Canonical_Pathways REACTOME_SULFUR_AMINO_ACID_METABOLISM 24 39 1 -1.35236 -1.15975
All_Canonical_Pathways REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE 25 39 1 -1.33503 -1.14577
All_Canonical_Pathways KEGG_SELENOAMINO_ACID_METABOLISM 26 39 1 -1.31839 -1.13247
All_Canonical_Pathways REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE 26 39 1 -1.31839 -1.13247
KEGG_Pathways KEGG_RIBOSOME 88 39 3 -3.21216 -1.83195
KEGG_Pathways KEGG_CALCIUM_SIGNALING_PATHWAY 178 39 3 -2.33762 -1.25844
All_Immunologic_Signatures GSE17721_LPS_VS_POLYIC_6H_BMDC_DN 199 39 5 -4.45541 -1.24189
PANTHER_Pathways S-adenosylmethionine_biosynthesis 3 39 1 -2.24707 -1.16789
PANTHER_Pathways TCA_cycle 6 39 1 -1.94724 -1.16909
Reactome_Pathways REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX 74 39 6 -8.28832 -6.10934
Reactome_Pathways REACTOME_TRANSLATION 222 39 8 -8.13524 -6.25729
Reactome_Pathways REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S 84 39 6 -7.95301 -6.25115
Reactome_Pathways REACTOME_PEPTIDE_CHAIN_ELONGATION 153 39 6 -6.39552 -4.81860
Reactome_Pathways REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION 176 39 6 -6.03864 -4.55863
Reactome_Pathways REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE 179 39 6 -5.99576 -4.59493
Reactome_Pathways REACTOME_METABOLISM_OF_RNA 330 39 7 -5.60324 -4.26936
Reactome_Pathways REACTOME_METABOLISM_OF_PROTEINS 518 39 8 -5.33314 -4.05725
Reactome_Pathways REACTOME_METABOLISM_OF_MRNA 284 39 6 -4.84205 -3.61731
Reactome_Pathways REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION 169 39 5 -4.79626 -3.61729
Reactome_Pathways REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 176 39 5 -4.71127 -3.57369
Reactome_Pathways REACTOME_INFLUENZA_LIFE_CYCLE 203 39 5 -4.41414 -3.31435
Reactome_Pathways REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION 9 39 2 -3.90538 -2.84035
Reactome_Pathways REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS 10 39 2 -3.80899 -2.77614
Reactome_Pathways REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL 11 39 2 -3.72236 -2.71947
Reactome_Pathways REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY 11 39 2 -3.72236 -2.71947
Reactome_Pathways REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES 12 39 2 -3.64370 -2.69517
Reactome_Pathways REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING 12 39 2 -3.64370 -2.69517
Reactome_Pathways REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR 12 39 2 -3.64370 -2.69517
Reactome_Pathways REACTOME_P75NTR_SIGNALS_VIA_NFKB 14 39 2 -3.50524 -2.62729
Reactome_Pathways REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON 14 39 2 -3.50524 -2.62729
Reactome_Pathways REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX 14 39 2 -3.50524 -2.62729
Reactome_Pathways REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING 14 39 2 -3.50524 -2.62729
Reactome_Pathways REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX 14 39 2 -3.50524 -2.62729
Reactome_Pathways REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS 15 39 2 -3.44361 -2.66257
Reactome_Pathways REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION 16 39 2 -3.38613 -2.62213
Reactome_Pathways REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR 18 39 2 -3.28166 -2.53405
Reactome_Pathways REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA 18 39 2 -3.28166 -2.53405
Reactome_Pathways REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY 20 39 2 -3.18864 -2.47206
Reactome_Pathways REACTOME_SIGNALING_BY_ERBB4 90 39 3 -3.18368 -2.48183
Reactome_Pathways REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING 23 39 2 -3.06583 -2.37821
Reactome_Pathways REACTOME_SIGNALING_BY_ERBB2 101 39 3 -3.03807 -2.36424
Reactome_Pathways REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN 25 39 2 -2.99286 -2.33240
Reactome_Pathways REACTOME_FANCONI_ANEMIA_PATHWAY 25 39 2 -2.99286 -2.33240
Reactome_Pathways REACTOME_EGFR_DOWNREGULATION 25 39 2 -2.99286 -2.33240
Reactome_Pathways REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS 26 39 2 -2.95862 -2.33594
Reactome_Pathways REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B 26 39 2 -2.95862 -2.33594
Reactome_Pathways REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION 27 39 2 -2.92571 -2.32652
Reactome_Pathways REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT 27 39 2 -2.92571 -2.32652
Reactome_Pathways REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS 27 39 2 -2.92571 -2.32652
Reactome_Pathways REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A 28 39 2 -2.89405 -2.32785
Reactome_Pathways REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING 31 39 2 -2.80564 -2.24991
Reactome_Pathways REACTOME_INNATE_IMMUNE_SYSTEM 279 39 4 -2.73136 -2.18586
Reactome_Pathways REACTOME_NEGATIVE_REGULATION_OF_FGFR_SIGNALING 37 39 2 -2.65272 -2.11720
Reactome_Pathways REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER 38 39 2 -2.62976 -2.10400
Reactome_Pathways REACTOME_G1_PHASE 38 39 2 -2.62976 -2.10400
Reactome_Pathways REACTOME_APOPTOSIS 148 39 3 -2.56267 -2.05579
Reactome_Pathways REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION 46 39 2 -2.46591 -1.96818
Reactome_Pathways REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 48 39 2 -2.42958 -1.94080
Reactome_Pathways REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT 51 39 2 -2.37793 -1.89792
Reactome_Pathways REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 51 39 2 -2.37793 -1.89792
Reactome_Pathways REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 51 39 2 -2.37793 -1.89792
Reactome_Pathways REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G 52 39 2 -2.36141 -1.90671
Reactome_Pathways REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 53 39 2 -2.34522 -1.89864
Reactome_Pathways REACTOME_CIRCADIAN_CLOCK 53 39 2 -2.34522 -1.89864
Reactome_Pathways REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX 56 39 2 -2.29850 -1.86771
Reactome_Pathways REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 56 39 2 -2.29850 -1.86771
Reactome_Pathways REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE 57 39 2 -2.28351 -1.86796
Reactome_Pathways REACTOME_REGULATION_OF_APOPTOSIS 58 39 2 -2.26878 -1.86066
Reactome_Pathways REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE 60 39 2 -2.24012 -1.83929
Reactome_Pathways REACTOME_ER_PHAGOSOME_PATHWAY 61 39 2 -2.22615 -1.83251
Reactome_Pathways REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX 63 39 2 -2.19893 -1.81235
Reactome_Pathways REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS 64 39 2 -2.18566 -1.80603
Reactome_Pathways REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C 64 39 2 -2.18566 -1.80603
Reactome_Pathways REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ 65 39 2 -2.17261 -1.80654
Reactome_Pathways REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX 65 39 2 -2.17261 -1.80654
Reactome_Pathways REACTOME_SIGNALING_BY_WNT 65 39 2 -2.17261 -1.80654
Reactome_Pathways REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES 66 39 2 -2.15976 -1.81329
Reactome_Pathways REACTOME_ORC1_REMOVAL_FROM_CHROMATIN 67 39 2 -2.14711 -1.80698
Reactome_Pathways REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 212 39 3 -2.12784 -1.79396
Reactome_Pathways REACTOME_SIGNALING_BY_NOTCH1 70 39 2 -2.11033 -1.78261
Reactome_Pathways REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 72 39 2 -2.08672 -1.76507
Reactome_Pathways REACTOME_NFKB_AND_MAP_KINASES_ACTIVATION_MEDIATED_BY_TLR4_SIGNALING_REPERTOIRE 72 39 2 -2.08672 -1.76507
Reactome_Pathways REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS 73 39 2 -2.07517 -1.76542
Reactome_Pathways REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS 73 39 2 -2.07517 -1.76542
Reactome_Pathways REACTOME_TRIF_MEDIATED_TLR3_SIGNALING 74 39 2 -2.06379 -1.76562
Reactome_Pathways REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION 76 39 2 -2.04150 -1.74901
Reactome_Pathways REACTOME_TRAF6_MEDIATED_INDUCTION_OF_NFKB_AND_MAP_KINASES_UPON_TLR7_8_OR_9_ACTIVATION 77 39 2 -2.03058 -1.74370
Reactome_Pathways REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING 81 39 2 -1.98837 -1.70702
Reactome_Pathways REACTOME_M_G1_TRANSITION 81 39 2 -1.98837 -1.70702
Reactome_Pathways REACTOME_MYD88_MAL_CASCADE_INITIATED_ON_PLASMA_MEMBRANE 83 39 2 -1.96808 -1.69759
Reactome_Pathways REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS 84 39 2 -1.95813 -1.69297
Reactome_Pathways REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE 85 39 2 -1.94831 -1.68841
Reactome_Pathways REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 251 39 3 -1.92878 -1.67408
Reactome_Pathways REACTOME_SYNTHESIS_OF_DNA 92 39 2 -1.88278 -1.63322
Reactome_Pathways REACTOME_ACTIVATED_TLR4_SIGNALLING 93 39 2 -1.87385 -1.62937
Reactome_Pathways REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR 97 39 2 -1.83913 -1.59968
Reactome_Pathways REACTOME_SIGNALING_BY_NOTCH 103 39 2 -1.78982 -1.55533
Reactome_Pathways REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 104 39 2 -1.78190 -1.55232
Reactome_Pathways REACTOME_SIGNALING_BY_EGFR_IN_CANCER 109 39 2 -1.74349 -1.51876
Reactome_Pathways REACTOME_S_PHASE 109 39 2 -1.74349 -1.51876
Reactome_Pathways REACTOME_SIGNALING_BY_FGFR 112 39 2 -1.72134 -1.50615
Reactome_Pathways REACTOME_DNA_REPAIR 112 39 2 -1.72134 -1.50615
Reactome_Pathways REACTOME_G1_S_TRANSITION 112 39 2 -1.72134 -1.50615
Reactome_Pathways REACTOME_TOLL_RECEPTOR_CASCADES 118 39 2 -1.67889 -1.47764
Reactome_Pathways REACTOME_CELL_CYCLE_CHECKPOINTS 124 39 2 -1.63871 -1.44200
Reactome_Pathways REACTOME_HIV_LIFE_CYCLE 125 39 2 -1.63221 -1.44001
Reactome_Pathways REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR 126 39 2 -1.62578 -1.43803
Reactome_Pathways REACTOME_SIGNALING_BY_FGFR_IN_DISEASE 127 39 2 -1.61939 -1.43605
Reactome_Pathways REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING 13 39 1 -1.61424 -1.43527
Reactome_Pathways REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION 13 39 1 -1.61424 -1.43527
Reactome_Pathways REACTOME_MEMBRANE_TRAFFICKING 129 39 2 -1.60679 -1.43642
Reactome_Pathways REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS 132 39 2 -1.58828 -1.42214
Reactome_Pathways REACTOME_MITOTIC_G1_G1_S_PHASES 137 39 2 -1.55843 -1.39648
Reactome_Pathways REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE 15 39 1 -1.55289 -1.39511
Reactome_Pathways REACTOME_IMMUNE_SYSTEM 933 39 5 -1.52034 -1.36667
Reactome_Pathways REACTOME_INFLAMMASOMES 17 39 1 -1.49933 -1.34974
Reactome_Pathways REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS 18 39 1 -1.47491 -1.32936
Reactome_Pathways REACTOME_CGMP_EFFECTS 19 39 1 -1.45183 -1.31028
Reactome_Pathways REACTOME_INTERFERON_SIGNALING 159 39 2 -1.43987 -1.30229
Reactome_Pathways REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING 20 39 1 -1.42995 -1.29629
Reactome_Pathways REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING 22 39 1 -1.38935 -1.25959
Reactome_Pathways REACTOME_MITOTIC_M_M_G1_PHASES 172 39 2 -1.37803 -1.25213
Reactome_Pathways REACTOME_SULFUR_AMINO_ACID_METABOLISM 24 39 1 -1.35236 -1.23029
Reactome_Pathways REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE 25 39 1 -1.33503 -1.21675
Reactome_Pathways REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE 26 39 1 -1.31839 -1.20387
BioCarta_Pathways BIOCARTA_EIF_PATHWAY 16 39 1 -1.52526 -1.04814
BioCarta_Pathways BIOCARTA_IGF1MTOR_PATHWAY 20 39 1 -1.42995 -1.03201
BioCarta_Pathways BIOCARTA_MITOCHONDRIA_PATHWAY 21 39 1 -1.40916 -1.07816
BioCarta_Pathways BIOCARTA_HER2_PATHWAY 22 39 1 -1.38935 -1.11635
BioCarta_Pathways BIOCARTA_CASPASE_PATHWAY 23 39 1 -1.37044 -1.14860
Cancer_Gene_Neighborhoods MORF_TPT1 102 39 4 -4.39178 -2.53445
Cancer_Gene_Neighborhoods MORF_ACTG1 138 39 4 -3.88106 -2.32476
Cancer_Gene_Neighborhoods MORF_NPM1 162 39 4 -3.61380 -2.23359
Cancer_Gene_Neighborhoods MORF_NME2 154 39 3 -2.51393 -1.25866
Cancer_Gene_Neighborhoods MORF_JUND 64 39 2 -2.18566 -1.02730
Cancer_Gene_Neighborhoods GCM_TPT1 70 39 2 -2.11033 -1.03115
Chemical_and_Genetic_Perturbations LIU_NASOPHARYNGEAL_CARCINOMA 70 39 3 -3.50401 -1.10694
Chemical_and_Genetic_Perturbations KIM_MYC_AMPLIFICATION_TARGETS_UP 201 39 4 -3.25885 -1.03787