陈恳 (18级直博)

陈恳

简历

  • 2014.9-2018.6 北京师范大学, 学士
  • 2018.9 至今 中山大学, 计算机学院, 直博

奖励

  1. Critical Assessment of Genome Interpretation (CAGI)-6 Sherloc clinical classification, Champion.
  2. CAGI-5 Vex-seq prediction，Ranked the 2nd.

Publications

  1. Chen K, Y Zhou, M Ding, Y Wang, Z Ren, Yuedong Yang*. Self-supervised learning on millions of pre-mRNA sequences improves sequence-based RNA splicing prediction. bioRxiv, 2023.01. 31.526427
  2. Chen K, Zhao H, Yuedong Yang*. Capturing large genomic contexts for accurately predicting enhancer-promoter interactions. Brief in Bioinfo 2022; https://doi.org/10.1093/bib/bbab577.
  3. Liu W#, Chen L#, Chen K#, Wu J#, Peng R, Tang Y, Chen J, Yuedong Yang*, P Li*, Z Huang*. Identification of novel single nucleotide variants with potential of mediating malfunction of microRNA in congenital heart disease. Front Cardiovasc Med 2021. https://www.frontiersin.org/articles/10.3389/fcvm.2021.739598/abstract
  4. Chen K, Lu Y, Zhao H, Yuedong Yang*. Predicting the change of exon splicing caused by genetic variant using support vector regression. Hum Mutat. 2019 Sep;40(9):1235-1242. https://onlinelibrary.wiley.com/doi/abs/10.1002/humu.23785.
  5. Fan C, Chen K, Zhou J, Wong PP, He D, Huang Y, Wang X, Ling T, Yang Y, Zhao H. Systematic analysis to identify transcriptome-wide dysregulation of Alzheimer's disease in genes and isoforms. Hum Genet. 2021 Apr;140(4):609-623. doi: 10.1007/s00439-020-02230-7.
  6. Mount SM, Avsec Ž, Carmel L, Casadio R, Çelik MH, Chen K, Cheng J, Cohen NE, Fairbrother WG, Fenesh T, Gagneur J, Gotea V, Holzer T, Lin CF, Martelli PL, Naito T, Nguyen TYD, Savojardo C, Unger R, Wang R, Yang Y, Zhao H. Assessing predictions of the impact of variants on splicing in CAGI5. Hum Mutat. 2019 Sep;40(9):1215-1224. doi: 10.1002/humu.23869.
  7. Qi M, Fan S, Wang Z, Yang X, Xie Z, Chen K, Zhang L, Lin T, Liu W, Lin X, Yan Y, Yang Y, Zhao H. Identifying Common Genes, Cell Types and Brain Regions Between Diseases of the Nervous System. Front Genet. 2019 Nov 29;10:1202. doi: 10.3389/fgene.2019.01202.
  8. Yan Y, Long T, Su Q, Wang Y, Chen K, Yang T, Zhao G, Ma Q, Hu X, Liu C, Liao X, Min W, Li S, Zhang D, Yang Y, Pu WT, Dong Y, Wang DZ, Chen Y, Huang ZP. Cardiac ISL1-Interacting Protein, a Cardioprotective Factor, Inhibits the Transition From Cardiac Hypertrophy to Heart Failure. Front Cardiovasc Med. 2022 Mar 17;9:857049. doi: 10.3389/fcvm.2022.857049.