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scRNA-seq/Pharmogenomics

  • Integrating and formatting biomedical data as pre-calculated knowledge graph embeddings in the Bioteque
  • Gene expression based inference of cancer drug sensitivity
  • Connecting omics signatures and revealing biological mechanisms with iLINCS
  • Computational pharmacogenomic screen identifies drugs that potentiate the anti-breast cancer activity of statins
  • SpotClean adjusts for spot swapping in spatial transcriptomics data
  • ORIGINS: a protein network-based approach to quantify cell pluripotency from scRNA-seq data. Daniela Senra, Nara Guisoni, and Luis Diambra. bioRxiv posted 10 May 2022 doi:10.1101/2022.05.09.491232
  • Stardust: improving spatial transcriptomics data analysis through space aware modularity optimization based clustering. Simone Avesani, Eva Viesi, Luca Alessandr&igrave, Giovanni Motterle, Vincenzo Bonnici, Marco Beccuti, Raffaele Calogero, and Rosalba Giugno. bioRxiv posted 10 May 2022 doi:10.1101/2022.04.27.489655
  • Explainable multiview framework for dissecting spatial relationships from highly multiplexed data Jovan Tanevski, Ricardo Omar Ramirez Flores, Attila Gabor, Denis Schapiro & Julio Saez-Rodriguez 德国
  • Systematic evaluation of colorectal cancer organoid system by single-cell RNA-Seq analysis Rui Wang, Yunuo Mao, Wendong Wang, Xin Zhou, Wei Wang, Shuai Gao, Jingyun Li, Lu Wen, Wei Fu & Fuchou Tang
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